Ballard Nancy, Robley Lois, Barrett Darcy, Fraser Danielle, Mendoza Inocencia
WellStar Health System, Marietta, GA, USA.
Am J Crit Care. 2006 Jan;15(1):86-94; quiz 95.
Neuromuscular blocking agents used for therapeutic purposes, such as facilitating mechanical ventilation and relieving life-threatening agitation, paralyze patients but leave them fully conscious. Aggressive sedation or analgesia is necessary to reduce awareness, relieve fear, produce comfort, decrease anxiety, induce unconsciousness, and minimize possible complications such as posttraumatic stress syndrome. Little information is available on the extent to which patients experience awareness during therapeutic paralysis.
To determine and describe the remembered experiences of critical care patients who were given neuromuscular blocking agents and sedatives and/or analgesics to facilitate mechanical ventilation, improve hemodynamic stability, and improve oxygenation.
A phenomenological approach with in-depth interviews with 11 patients was used. Data were analyzed by using the constant comparative approach.
A total of 4 themes and 3 subthemes were identified. The first theme was back and forth between reality and the unreal, between life and death; the subtheme was having weird dreams. The second theme was loss of control; the 2 subthemes were (1) fighting or being tied down and (2) being scared. The third theme was almost dying, and the fourth theme was feeling cared for.
Patients can remember having both negative and positive experiences during neuromuscular blockade. Steps to improve the experiences of patients receiving neuromuscular blockers include improving assessment parameters, developing and using sedation/analgesia guidelines, and investing in quality improvement programs to provide assessment of awareness during therapeutic paralysis and follow-up and referral as necessary. Ways to decrease the use of neuromuscular blockers would also be useful.
用于治疗目的的神经肌肉阻滞剂,如促进机械通气和缓解危及生命的躁动,会使患者麻痹但意识完全清醒。积极的镇静或镇痛对于降低意识、减轻恐惧、产生舒适感、减少焦虑、诱导无意识以及将诸如创伤后应激综合征等可能的并发症降至最低是必要的。关于患者在治疗性麻痹期间意识体验程度的信息很少。
确定并描述接受神经肌肉阻滞剂以及镇静剂和/或镇痛药以促进机械通气、改善血流动力学稳定性和改善氧合的重症监护患者的记忆体验。
采用现象学方法,对11名患者进行深入访谈。使用持续比较法对数据进行分析。
共确定了4个主题和3个子主题。第一个主题是在现实与虚幻、生与死之间来回切换;子主题是做怪梦。第二个主题是失去控制;两个子主题分别是(1)挣扎或被束缚以及(2)感到害怕。第三个主题是濒死体验,第四个主题是感觉受到关怀。
患者能够记住在神经肌肉阻滞期间既有负面经历也有正面经历。改善接受神经肌肉阻滞剂患者体验的措施包括改进评估参数、制定和使用镇静/镇痛指南,以及投入质量改进项目以在治疗性麻痹期间评估意识并在必要时进行随访和转诊。减少神经肌肉阻滞剂使用的方法也会很有用。