Basta-Jovanović Gordana, Radojević Sanja, Savin Marina, Terzić Tatjana, Nenadović Maja, Stojimirović Biljana, Skodrić Stevo, Nesić Vidosava, Dikman Steve
Institute of Pathology, School of Medicine, University of Belgrade.
Srp Arh Celok Lek. 2005 May-Jun;133(5-6):258-61. doi: 10.2298/sarh0506258b.
HIV-infected patients may be faced with a variety of renal problem patterns. HIV-associated nephropathy is a unique pattern of sclerosing glomerulopathy and represents the most rapidly progressive form of focal segmental glomerulosclerosis. This study involved the examination of 32 renal biopsies: by light, immunofluorescence, and electron microscopy, in order to determine the most accurate and reliable diagnostic procedure. The findings show that the most sensitive and accurate procedure is electron microscopy, capable of detecting specific EM changes very early on, which is sufficient for the diagnosis of HIV-associated nephropathy.
感染HIV的患者可能面临多种肾脏问题模式。HIV相关性肾病是一种独特的硬化性肾小球病模式，是局灶节段性肾小球硬化最快速进展的形式。本研究对32例肾活检组织进行了检查：采用光镜、免疫荧光和电子显微镜检查，以确定最准确可靠的诊断方法。研究结果表明，最敏感准确的方法是电子显微镜检查，它能够在早期检测到特定的电子显微镜变化，这足以诊断HIV相关性肾病。
