Suppr超能文献

[重新使用阿托伐他汀后发生的急性胆汁淤积性肝炎]

[Acute cholestatic hepatitis after atorvastatin reintroduction].

作者信息

de Castro M L, Hermo J A, Baz A, de Luaces C, Pérez R, Clofent J

机构信息

Servicio de Aparato Digestivo, Hospital Meixoeiro-CHUVI Vigo, Pontevedra, Spain.

出版信息

Gastroenterol Hepatol. 2006 Jan;29(1):21-4. doi: 10.1157/13083248.

Abstract

Consumption of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA) inhibitors, known as statins, has been associated with elevated transaminase levels but rarely with acute hepatitis. Recently, several cases of acute hepatitis secondary to atorvastatin therapy have been published. We report the case of a 72-year-old man who developed acute cholestatic hepatitis after reinitiating treatment with atorvastatin at a higher dose than that previously prescribed. After treatment discontinuation, the patient made a full recovery, with normalization of clinical and laboratory findings.

摘要

服用3-羟基-3-甲基戊二酰辅酶A还原酶(HMG-CoA)抑制剂(即他汀类药物)与转氨酶水平升高有关,但很少引发急性肝炎。最近,已有几例继发于阿托伐他汀治疗的急性肝炎病例发表。我们报告了一例72岁男性患者的病例,该患者在重新开始服用比之前处方剂量更高的阿托伐他汀后出现了急性胆汁淤积性肝炎。停药后,患者完全康复,临床和实验室检查结果恢复正常。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验