Biswas G, Khadwal A, Kulkarni P, Bakshi A, Nair C, Kurkure P, Muckaden M, Parikh P
Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
Indian J Dermatol Venereol Leprol. 2005 Nov-Dec;71(6):423-5. doi: 10.4103/0378-6323.18950.
Ewing's sarcoma (ES) is a small round cell tumor, usually arising from flat bones and diaphyseal region of long bones. It is commonly found in the first two decades of life. It is curable when diagnosed in the localized stage and requires multimodality treatment. ES is a chemosensitive tumor. It metastasizes commonly to lung, pleura and other bones. Less common sites of metastasis are lymph nodes, CNS and liver. Skin metastasis is extremely uncommon. It occurs in up to 9% of all patients with cancer. Growth pattern of cutaneous metastasis is unpredictable and may not reflect that of primary tumor. We hereby report three cases of Ewing's sarcoma that developed skin metastasis.
尤因肉瘤（ES）是一种小圆细胞肿瘤，通常起源于扁骨和长骨的骨干区域。它常见于生命的前二十年。在局部阶段诊断出来时是可治愈的，并且需要多模式治疗。ES是一种对化疗敏感的肿瘤。它通常转移至肺、胸膜和其他骨骼。较少见的转移部位是淋巴结、中枢神经系统和肝脏。皮肤转移极其罕见。它发生在所有癌症患者中的比例高达9%。皮肤转移的生长模式不可预测，可能无法反映原发肿瘤的生长模式。我们在此报告三例发生皮肤转移的尤因肉瘤病例。
