Jacobs V R, Niemeyer M, Gottschalk N, Schneider K T, Kiechle M
Frauen- und Poliklinik, Klinikum rechts der Isar, Technische Universität München.
Z Geburtshilfe Neonatol. 2005 Dec;209(6):223-7. doi: 10.1055/s-2005-916246.
Private umbilical cord blood (UCB) banking after delivery has increased over the last decade. For adult/somatic stem cell research UCB is an essential source of stem cells and researchers question if the number of UCB samples for research might be reduced by private banking.
A survey among seven private blood banks in Germany and analysis and comparison of the number of UCB samples donated for research within the STEMMAT project with private blood banking were performed from 03/2003 to 06/2005 at the Frauenklinik (OB/GYN), Technical University Munich, Germany.
Within 27.5 months 1,551 UCB samples were collected for research purposes; the effective recruitment rate was higher than expectations at an effective 66.2 %. Private UCB banking [n = 24] was distributed among three cord blood banks [n = 16, 6 and 4]. The rate of private blood banking was 0.99 % for all deliveries, thus reducing the effective rate for research purpose by only 1.5 %.
Under the assumption of active and successful recruitment of scientific UCB samples, private blood banking does not significantly reduce this rate and therefore is a negligible rival in the competition for sufficient numbers of UCB samples for research.
在过去十年中,产后私人脐带血储存量有所增加。对于成人/体细胞干细胞研究而言,脐带血是干细胞的重要来源,研究人员质疑私人储存脐带血样本是否会减少用于研究的脐带血样本数量。
2003年3月至2005年6月期间,在德国慕尼黑工业大学妇产科医院对德国七家私人血库进行了一项调查,并对STEMMAT项目中捐赠用于研究的脐带血样本数量与私人脐带血储存情况进行了分析和比较。
在27.5个月内,共采集了1551份用于研究目的的脐带血样本;有效招募率高于预期,达到了66.2%。私人脐带血储存(n = 24)分布在三家脐带血库中(n = 16、6和4)。所有分娩中私人脐带血储存率为0.99%,因此仅使用于研究目的的有效率降低了1.5%。
在积极且成功招募用于科研的脐带血样本的前提下,私人脐带血储存并不会显著降低这一比例,因此在争夺足够数量用于研究的脐带血样本的竞争中,它是一个可以忽略不计的对手。