Amon Joseph J, Darling Natalie, Fiore Anthony E, Bell Beth P, Barker Lawrence E
Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Pediatrics. 2006 Jan;117(1):30-3. doi: 10.1542/peds.2005-0286.
In 1999, the Advisory Committee on Immunization Practices made recommendations for hepatitis A vaccination of children according to historic rates of hepatitis A incidence in different regions of the country. The objective of this study was to examine hepatitis A vaccination coverage rates among children living in states with different vaccination recommendations and to examine individual characteristics associated with vaccination.
Hepatitis A vaccination status data were collected for children 24 to 35 months of age through the National Immunization Survey, a telephone survey with health care provider-verified vaccination results. Vaccination status data were collected from children in each of the 50 states and 28 selected urban areas.
In 2003, 50.9% (95% confidence interval [CI]: 47.6-54.2%) of children living in 11 states where routine hepatitis A vaccination is recommended had received > or =1 dose, compared with 25.0% (95% CI: 21.8-28.2%) of children in 6 states where vaccination is suggested and 1.4% (95% CI: 1.0-1.8%) of children in 33 states without a recommendation. Coverage was higher among children who lived in urban areas, were Hispanic or American Indian/Alaska Native, or were born to women with less education.
Hepatitis A vaccination is being targeted successfully to children at higher risk of infection; however, overall vaccination coverage remains lower for hepatitis A vaccination, compared with other routine childhood vaccinations.
1999年,免疫实践咨询委员会根据美国不同地区甲型肝炎的历史发病率,对儿童甲型肝炎疫苗接种提出了建议。本研究的目的是调查生活在不同疫苗接种建议州的儿童的甲型肝炎疫苗接种覆盖率,并调查与疫苗接种相关的个体特征。
通过国家免疫调查收集24至35个月龄儿童的甲型肝炎疫苗接种状况数据,这是一项通过电话调查且疫苗接种结果经医疗保健提供者核实的调查。从50个州和28个选定城市地区的儿童中收集疫苗接种状况数据。
2003年,在建议进行常规甲型肝炎疫苗接种的11个州,50.9%(95%置信区间[CI]:47.6 - 54.2%)的儿童接种了≥1剂疫苗,相比之下,在建议接种疫苗的6个州,这一比例为25.0%(95% CI:21.8 - 28.2%),在未给出建议的33个州,这一比例为1.4%(95% CI:1.0 - 1.8%)。城市地区儿童、西班牙裔或美国印第安/阿拉斯加原住民儿童,或母亲受教育程度较低的儿童的接种覆盖率更高。
甲型肝炎疫苗接种已成功针对感染风险较高的儿童;然而,与其他常规儿童疫苗接种相比,甲型肝炎疫苗的总体接种覆盖率仍然较低。