Lieberman Jay M, Word Bonnie M, Jacobs R Jake, Dagan Ron, Marchant Colin D
University of California, Irvine School of Medicine, Irvine, CA, USA.
Pediatr Infect Dis J. 2008 Apr;27(4):287-91. doi: 10.1097/INF.0b013e31815efe4b.
Previous hepatitis A recommendations for the United States targeted vaccination of at-risk individuals and children living in states and communities with consistently elevated rates of hepatitis A. Recommendations now call for routine hepatitis A vaccination of all children in the United States beginning at age 1 year (12-23 months). Currently, vaccination coverage rates for hepatitis A remain below rates of other routine childhood vaccines. Achieving a national immunization rate greater than 90% for the recommended 2 doses of hepatitis A vaccine would lessen disease impact throughout society. Routine childhood immunization against hepatitis A can be a highly effective strategy to reduce infection in children and community transmission of the virus, and the elimination of indigenous transmission of hepatitis A is an attainable goal.
美国先前关于甲型肝炎的建议是针对高危人群以及生活在甲型肝炎发病率持续较高的州和社区的儿童进行疫苗接种。现在的建议要求美国所有儿童从1岁（12至23个月）起常规接种甲型肝炎疫苗。目前，甲型肝炎疫苗的接种覆盖率仍低于其他常规儿童疫苗的接种率。实现推荐的2剂甲型肝炎疫苗全国免疫率超过90%将减轻疾病对整个社会的影响。儿童常规接种甲型肝炎疫苗是减少儿童感染和病毒社区传播的一项非常有效的策略，消除甲型肝炎的本土传播是一个可以实现的目标。
