Herzog W, Kamal S, Clarke H D
Human Performance Laboratory, Faculty of Physical Education, University of Calgary, AB, Canada.
J Biomech. 1992 Aug;25(8):945-8. doi: 10.1016/0021-9290(92)90235-s.
The cat is the primary model for neuromuscular research. However, sarcomere geometry, in particular thin-myofilament lengths of cat skeletal muscles, is not known, thus preventing adequate muscle modeling on the sarcomere level. The purpose of this study was to determine thin-myofilament lengths in cat skeletal muscle. It was found that average thin-myofilament lengths of cat tibialis anterior muscles (1.12 microns) were larger than the average values reported for frog (approximately 0.95 microns), rat (1.09 microns), and rabbit muscles (1.09 microns) and were smaller than the values reported for monkey (1.16 microns) and human skeletal muscles (1.27 microns). According to the cross-bridge theory of muscular contraction, this result implies that the range of sarcomere length on the ascending limb of the force-length relation for cat muscle is between those of frog, rat, and rabbit on the one side and monkey and human on the other side. It is speculated that the differences in thin-myofilament lengths of different animals are related to the functional demands of these muscles in everyday movement tasks. Isolated experimental observations appear to support this speculation.
猫是神经肌肉研究的主要模型。然而，肌节几何结构，尤其是猫骨骼肌细肌丝的长度尚不清楚，因此无法在肌节水平上进行充分的肌肉建模。本研究的目的是确定猫骨骼肌中的细肌丝长度。研究发现，猫胫骨前肌的平均细肌丝长度（1.12微米）大于青蛙（约0.95微米）、大鼠（1.09微米）和兔子肌肉（1.09微米）的报告平均值，且小于猴子（1.16微米）和人类骨骼肌（1.27微米）的报告值。根据肌肉收缩的横桥理论，这一结果意味着猫肌肉力-长度关系上升支上的肌节长度范围，一侧介于青蛙、大鼠和兔子之间，另一侧介于猴子和人类之间。据推测，不同动物细肌丝长度的差异与这些肌肉在日常运动任务中的功能需求有关。孤立的实验观察结果似乎支持这一推测。
