Platisa Mirjana M, Nestorovic Zorica, Damjanovic Svetozar, Gal Vera
Institute of Biophysics, Faculty of Medicine, Belgrade University, Belgrade, Serbia and Montenegro.
Clin Physiol Funct Imaging. 2006 Jan;26(1):54-60. doi: 10.1111/j.1475-097X.2005.00653.x.
Previous results on heart rate variability (HRV) analysis in anorexia nervosa (AN) include some apparently conflicting data. In order to find out the reason for different results and to improve understanding of autonomic control in AN we compare HRV in acute and chronic AN. Spectral powers, fractal scaling exponent and sample entropy were computed from 24 h RR series derived from Holter ECG recordings in 17 anorexic patients, nine chronic and eight healthy women. We found that all linear and non-linear HRV measures change in different direction in acute and chronic AN. Acute AN is characterized by decreased HR and increased HRV. In chronic AN, HR is increased, HRV reduced and the difference between awake and sleeping values is high. HRV measures are associated with body mass index only in chronic AN. As HRV measures are significantly different between acute and chronic AN, we propose that HRV analysis might provide additional data in clinical practice.
先前关于神经性厌食症（AN）心率变异性（HRV）分析的结果包含一些明显相互矛盾的数据。为了找出结果不同的原因并增进对AN自主控制的理解，我们比较了急性和慢性AN患者的HRV。从17名厌食症患者、9名慢性患者和8名健康女性的动态心电图记录得出的24小时RR序列中计算频谱功率、分形缩放指数和样本熵。我们发现，在急性和慢性AN中，所有线性和非线性HRV指标都朝着不同方向变化。急性AN的特征是心率降低和HRV增加。在慢性AN中，心率增加，HRV降低，清醒和睡眠值之间的差异很大。HRV指标仅在慢性AN中与体重指数相关。由于急性和慢性AN之间的HRV指标存在显著差异，我们认为HRV分析可能会在临床实践中提供更多数据。
