Human microsomal prostaglandin E synthase 1: a member of the MAPEG protein superfamily.
作者信息
Pettersson Pär L, Thorén Staffan, Jakobsson Per-Johan
机构信息
Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
出版信息
Methods Enzymol. 2005;401:147-61. doi: 10.1016/S0076-6879(05)01009-8.
Abstract
In this chapter, we briefly review the MAPEG superfamily (membrane associated proteins in eicosanoid and glutathione metabolism), a family of proteins in which all human members except one possess glutathione conjugating capacity. Recent findings regarding the biological functions of MAPEG proteins are highlighted. More extensively, the characterization of human microsomal prostaglandin E synthase 1 is presented, including results and applied methodology.
摘要
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