Sparchez Zeno
3rd Medical Clinic, University of Medicine and Pharmacy, Str. Croitorilor no. 19-21, 400162 Cluj-Napoca, Romania.
Rom J Gastroenterol. 2005 Dec;14(4):379-84.
Liver biopsy is nowadays a well established procedure in the diagnosis and follow up of liver disease. It is indicated in various clinical settings to establish a diagnosis, to assess prognosis and to monitor therapy. Complications are infrequent, most of them being minor (pain and vasovagal reaction). Major complications occur less frequently, the most important being bleeding. Several factors are associated with the tendency to bleed: coagulation abnormality, presence of liver cirrhosis or malignancy, inexperienced operator, blind technique and increased number of passes. Ultrasound guided liver biopsy is nowadays a very debated issue. It has been demonstrated that it decreases the rate of both minor and major complications after liver biopsy and it is cost effective. Outpatient liver biopsy has gained more acceptance today, being well-accepted by the patients and less costly.
如今,肝活检在肝病的诊断和随访中是一种成熟的检查方法。在各种临床情况下,它可用于明确诊断、评估预后以及监测治疗。并发症并不常见,大多数为轻微并发症(疼痛和血管迷走神经反应)。严重并发症发生频率较低,其中最重要的是出血。有几个因素与出血倾向相关:凝血异常、肝硬化或恶性肿瘤的存在、操作人员经验不足、盲目操作技术以及穿刺次数增加。如今,超声引导下肝活检是一个备受争议的问题。已经证明,它可降低肝活检后轻微和严重并发症的发生率,并且具有成本效益。门诊肝活检如今越来越被接受,受到患者的广泛认可且成本更低。