Kenny B G, Hitchcock E R, Kitchen G, Dalton A E, Yates D A, Chavda S V
University of Birmingham, Midland Centre for Neurosurgery and Neurology, UK.
J Neurol Neurosurg Psychiatry. 1992 Jul;55(7):590-3. doi: 10.1136/jnnp.55.7.590.
Stereotactic linear accelerator (linac) radiosurgery has been in operation in the West Midlands since 1987, the first of its kind in the United Kingdom. Forty two patients with high-flow cerebral arteriovenous malformations have been treated, 26 of whom have been followed up. Angiography one year after treatment showed that five lesions were obliterated, 11 were reduced in size and/or flow rate and 10 were unchanged. Overall results show that nine out of 10 patients reviewed at 24 months had total obliteration. Three patients had complications; one has fully recovered, one died of an unrelated cause at 36 months and the other died from recurrent haemorrhage at nine months. Two patients had recurrent non-fatal haemorrhage within 24 months of treatment; both recovered without further deficit. All patients are fit to work but eight are unemployed. Although the follow up period is short, the early results indicate a success rate similar to those published by others using linac radiosurgery.
自1987年起，立体定向直线加速器放射外科手术就在西米德兰兹郡开展，这在英国尚属首次。已对42例高流量脑动静脉畸形患者进行了治疗，其中26例接受了随访。治疗一年后的血管造影显示，5个病灶消失，11个病灶大小和/或血流速度减小，10个病灶无变化。总体结果显示，在24个月时接受复查的10例患者中有9例完全闭塞。3例患者出现并发症；1例已完全康复，1例在36个月时因无关原因死亡，另1例在9个月时死于复发性出血。2例患者在治疗后24个月内出现复发性非致命性出血；二者均康复且无进一步功能缺损。所有患者均适合工作，但有8人失业。尽管随访期较短，但早期结果表明成功率与其他使用直线加速器放射外科手术者公布的结果相似。
