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气管支气管残余所致先天性食管狭窄:一种与食管闭锁相关的罕见但重要的关联情况。

Congenital esophageal stenosis due to tracheobronchial remnants: a rare but important association with esophageal atresia.

作者信息

Yeung C K, Spitz L, Brereton R J, Kiely E M, Leake J

机构信息

Department of Paediatric, Hospital for Sick Children, London, England.

出版信息

J Pediatr Surg. 1992 Jul;27(7):852-5. doi: 10.1016/0022-3468(92)90382-h.

DOI:10.1016/0022-3468(92)90382-h
PMID:1640332
Abstract

Congenital esophageal stenosis caused by tracheobronchial remnants occurred in eight children, six of whom had associated esophageal atresia and/or tracheoesophageal fistula. Symptoms usually began in early infancy but delayed diagnosis was a common feature. The mean lag period between presentation and definitive operation was 4.6 years (range, 1 month to 16 years). Errors in diagnosis were common. Six were initially diagnosed as having inflammatory strictures secondary to reflux esophagitis. Seven children were subjected to repeated esophagoscopy and bouginage of the "stricture" (mean no. = 3.4), with invariable failure to ameliorate dysphagia. Antireflux procedures were performed in three patients. In all children, symptoms were dramatically relieved following resection of the stenotic segment or esophageal replacement. Although a rare entity, congenital esophageal stenosis due to tracheobronchial remnants should be considered a possibility in patients with esophageal stricture, presumed to be inflammatory in nature, which fails to respond to standard therapy.

摘要

由气管支气管残余物引起的先天性食管狭窄发生在8名儿童中,其中6名伴有食管闭锁和/或气管食管瘘。症状通常在婴儿早期开始,但延迟诊断是一个常见特征。从出现症状到最终手术的平均间隔时间为4.6年(范围为1个月至16年)。诊断错误很常见。6例最初被诊断为反流性食管炎继发的炎性狭窄。7名儿童接受了反复的食管镜检查和对“狭窄”的探条扩张术(平均次数=3.4次),但吞咽困难均未得到改善。3例患者进行了抗反流手术。在所有儿童中,切除狭窄段或进行食管置换后症状均显著缓解。尽管是一种罕见的疾病,但对于食管狭窄且被认为是炎性狭窄但对标准治疗无反应的患者,应考虑由气管支气管残余物引起的先天性食管狭窄的可能性。

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