Bliddal Henning, Christensen Robin D K
H:S Frederiksberg Hospital, Parker Instituttet, Frederiksberg.
Ugeskr Laeger. 2006 Jan 9;168(2):190-3.
Increases in both overweight and life expectancy of the population will lead to a larger number of patients with knee problems due to osteoarthritis (OA). Several changes, metabolic as well as functional, link obesity with OA. Randomised controlled trials have shown substantial and clinically relevant disability and symptom relief in obese patients with knee OA following moderate weight loss. While exercises are good for the functional status in general, it is advisable initially to prescribe weight loss as therapy of patients with a combination of obesity and OA.
超重人口数量的增加以及预期寿命的延长，将导致因骨关节炎（OA）而出现膝关节问题的患者数量增多。肥胖与骨关节炎之间存在多种代谢和功能方面的关联。随机对照试验表明，体重适度减轻后，肥胖的膝关节骨关节炎患者的残疾状况和症状得到了显著且具有临床意义的缓解。虽然运动总体上对功能状态有益，但对于肥胖且患有骨关节炎的患者，建议最初将减肥作为治疗方法。
