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正常血压和血糖正常的韩国男性的腹部肥胖、收缩压与微量白蛋白尿

Abdominal obesity, systolic blood pressure, and microalbuminuria in normotensive and euglycemic Korean men.

作者信息

Chang Y, Yoo T, Ryu S, Huh B Y, Cho B L, Sung E, Park M, Yoo S H

机构信息

Medical Screening Center, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Republic of Korea.

出版信息

Int J Obes (Lond). 2006 May;30(5):800-4. doi: 10.1038/sj.ijo.0803210.

DOI:10.1038/sj.ijo.0803210
PMID:16404402
Abstract

OBJECTIVES

To evaluate the relationship between abdominal obesity and microalbuminuria (MA) in normotensive, euglycemic Korean men.

DESIGN

A cross-sectional study at a health screening center.

SUBJECTS

A total of 1321 healthy, normotensive Korean men, aged 20-78 years, with a fasting plasma glucose level <100 mg/dl.

MEASUREMENTS

Height, weight, and waist; systolic blood pressure (SBP); diastolic blood pressures (DBP); urinary albumin to creatinine ratio (ACR); fasting glucose, insulin, lipids, C-reactive protein (CRP), and white blood cell count. Waist circumference (WC) was used to indicate abdominal obesity and a single measurement of ACR was used to estimate MA. We also calculated body mass index (BMI) based on weight and height.

RESULTS

Mean BMI, WC, and SBP were significantly higher in subjects with MA than in those without (24.8+/-4.1 vs 23.8+/-2.7 kg/m2, 86+/-9 vs 83+/-8 cm, and 115+/-5 vs 112+/-7 mmHg, respectively). Multiple logistic regression analyses showed that only WC and SBP were independent predictors of MA.

CONCLUSION

WC and SBP were positively associated with MA in normotensive and euglycemic Korean men.

摘要

目的

评估血压正常、血糖正常的韩国男性中腹型肥胖与微量白蛋白尿(MA)之间的关系。

设计

在一家健康筛查中心进行的横断面研究。

研究对象

共有1321名年龄在20 - 78岁之间、血压正常且空腹血糖水平<100 mg/dl的健康韩国男性。

测量指标

身高、体重和腰围;收缩压(SBP);舒张压(DBP);尿白蛋白与肌酐比值(ACR);空腹血糖、胰岛素、血脂、C反应蛋白(CRP)和白细胞计数。腰围(WC)用于指示腹型肥胖,单次测量ACR用于评估MA。我们还根据体重和身高计算了体重指数(BMI)。

结果

MA患者的平均BMI、WC和SBP显著高于无MA患者(分别为24.8±4.1 vs 23.8±2.7 kg/m²、86±9 vs 83±8 cm和115±5 vs 112±7 mmHg)。多因素逻辑回归分析显示,只有WC和SBP是MA的独立预测因素。

结论

在血压正常、血糖正常韩国男性中,WC和SBP与MA呈正相关。

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