Czauderna Piotr, Otte Jean-Bernard, Roebuck Derek J, von Schweinitz Dietrich, Plaschkes Jack
Department of Paediatric Surgery, Medical University of Gdansk, ul. Nowe Ogrody 1-6, Gdansk 80-803, Poland.
Pediatr Radiol. 2006 Mar;36(3):187-91. doi: 10.1007/s00247-005-0067-0. Epub 2006 Jan 11.
Hepatoblastoma is the most common liver malignancy in children. With rare exceptions, complete tumour resection is required to cure the patient. Radical tumour resection can be obtained either with standard partial hepatectomy or orthotopic liver transplantation. At present, the surgical approach to hepatoblastoma differs significantly between treatment groups in different parts of the world. Our aim was to review current surgical policy in hepatoblastoma. All aspects of surgery in hepatoblastoma are discussed, including biopsy, tumour resection principles, modern achievements in the field of liver surgery, and the indications and potential contraindications for liver transplantation. Every effort should be made to resect hepatoblastoma completely either by standard partial hepatectomy or by the use of liver transplantation in difficult or clearly unresectable cases.
肝母细胞瘤是儿童最常见的肝脏恶性肿瘤。除极少数例外情况,患者治愈需要完整切除肿瘤。根治性肿瘤切除可通过标准的部分肝切除术或原位肝移植实现。目前,世界各地不同治疗组对肝母细胞瘤的手术方式差异显著。我们的目的是回顾当前肝母细胞瘤的手术策略。本文讨论了肝母细胞瘤手术的各个方面,包括活检、肿瘤切除原则、肝脏手术领域的现代成果以及肝移植的适应证和潜在禁忌证。应尽一切努力通过标准的部分肝切除术完整切除肝母细胞瘤,对于困难或明显无法切除的病例则采用肝移植。