Herzog C E, Andrassy R J, Eftekhari F
University of Texas M.D. Anderson Cancer Center, University of Texas-Houston Medical School, Houston, Texas 77030, USA.
Oncologist. 2000;5(6):445-53. doi: 10.1634/theoncologist.5-6-445.
Hepatoblastoma is the most common primary liver tumor in children, accounting for just over 1% of pediatric cancers. The etiology is unknown, but it has been associated with Beckwith-Weidemann syndrome, familial adenomatosis polypi, and low birth weight. The primary treatment is surgical resection, however, chemotherapy plays an important role by increasing the number of tumors that are resectable. The prognosis for patients with resectable tumors is fairly good, however, the outcome for those with nonresectable or recurrent disease is poor.
肝母细胞瘤是儿童最常见的原发性肝脏肿瘤，占儿童癌症的比例略高于1%。其病因尚不清楚，但与贝克威思-维德曼综合征、家族性腺瘤性息肉病和低出生体重有关。主要治疗方法是手术切除，然而，化疗通过增加可切除肿瘤的数量发挥重要作用。可切除肿瘤患者的预后相当好，然而，不可切除或复发性疾病患者的结局较差。
