阿什肯纳兹犹太人的母系血统：近期奠基者事件的写照。
The matrilineal ancestry of Ashkenazi Jewry: portrait of a recent founder event.
作者信息
Behar Doron M, Metspalu Ene, Kivisild Toomas, Achilli Alessandro, Hadid Yarin, Tzur Shay, Pereira Luisa, Amorim Antonio, Quintana-Murci Lluis, Majamaa Kari, Herrnstadt Corinna, Howell Neil, Balanovsky Oleg, Kutuev Ildus, Pshenichnov Andrey, Gurwitz David, Bonne-Tamir Batsheva, Torroni Antonio, Villems Richard, Skorecki Karl
机构信息
Rappaport Faculty of Medicine and Research Institute, Technion and Rambam Medical Center, Haifa, Israel.
出版信息
Am J Hum Genet. 2006 Mar;78(3):487-97. doi: 10.1086/500307. Epub 2006 Jan 11.
Abstract
Both the extent and location of the maternal ancestral deme from which the Ashkenazi Jewry arose remain obscure. Here, using complete sequences of the maternally inherited mitochondrial DNA (mtDNA), we show that close to one-half of Ashkenazi Jews, estimated at 8,000,000 people, can be traced back to only 4 women carrying distinct mtDNAs that are virtually absent in other populations, with the important exception of low frequencies among non-Ashkenazi Jews. We conclude that four founding mtDNAs, likely of Near Eastern ancestry, underwent major expansion(s) in Europe within the past millennium.
摘要
阿什肯纳兹犹太人的母系祖先群落的范围和位置仍然不明。在此，我们使用母系遗传的线粒体DNA（mtDNA）的完整序列，表明近一半的阿什肯纳兹犹太人（估计有800万人）可以追溯到仅4名携带独特mtDNA的女性，这些mtDNA在其他人群中几乎不存在，但非阿什肯纳兹犹太人中有低频率存在这一重要例外。我们得出结论，四个奠基性的mtDNA，可能起源于近东，在过去一千年内在欧洲经历了主要的扩张。
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