Walker R D, Wilson J, Clark A E
Department of Surgery, University of Florida, Gainesville.
J Urol. 1992 Aug;148(2 Pt 2):645-7. doi: 10.1016/s0022-5347(17)36680-6.
Injectable polytetrafluoroethylene (Teflon) and collagen have inherent problems that may prevent their long-term success. In search of a different injectable biomaterial we confirmed in rabbits the safety of injected Bioglass particles suspended in sodium hyaluronate. A second study was performed testing the ability of the Bioglass suspension to increase urethral resistance in pigs. Bioglass particles in suspension have the potential to substitute for polytetrafluoroethylene or collagen in the treatment of urinary incontinence or vesicoureteral reflux.
可注射聚四氟乙烯（特氟龙）和胶原蛋白存在一些固有问题，这可能会妨碍它们取得长期成功。为寻找一种不同的可注射生物材料，我们在兔子身上证实了悬浮于透明质酸钠中的注射用生物活性玻璃颗粒的安全性。第二项研究对生物活性玻璃悬浮液增强猪尿道阻力的能力进行了测试。悬浮的生物活性玻璃颗粒有潜力在治疗尿失禁或膀胱输尿管反流中替代聚四氟乙烯或胶原蛋白。
