Rubegni P, Poggiali S, Sbano P, Risulo M, Fimiani M
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Italy.
J Eur Acad Dermatol Venereol. 2006 Jan;20(1):84-7. doi: 10.1111/j.1468-3083.2005.01352.x.
Tacrolimus is a macrolide that inhibits T-cell activation. The most extensive experience with topical tacrolimus has been in treating atopic dermatitis but it has been used in various skin diseases, including Hailey-Hailey disease, with encouraging results. We report a case of extensive Darier's disease successfully treated with topical tacrolimus, after suspension of oral isotretrinoin due to major depression.
他克莫司是一种抑制T细胞活化的大环内酯类药物。外用他克莫司最广泛的应用经验是治疗特应性皮炎，但它也已被用于各种皮肤病，包括黑利-黑利病，且取得了令人鼓舞的效果。我们报告了1例广泛性毛囊角化病，在因重度抑郁停用口服异维A酸后，外用他克莫司成功治愈。
Zotero 插件