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自闭症谱系中一个假设症状模型的结构方程分析。

Structural equation analysis of a hypothesised symptom model in the autism spectrum.

作者信息

van Lang Natasja D J, Boomsma Anne, Sytema Sjoerd, de Bildt Annelies A, Kraijer Dirk W, Ketelaars Cees, Minderaa Ruud B

机构信息

University of Groningen, Department of Child and Adolescent Psychiatry, The Netherlands.

出版信息

J Child Psychol Psychiatry. 2006 Jan;47(1):37-44. doi: 10.1111/j.1469-7610.2005.01434.x.

Abstract

BACKGROUND

Several studies showed a different symptom structure underlying the spectrum of autistic-like disorders from the behaviour triad as mentioned in the DSM-IV. In the present study, a hypothesised symptom model for autism was constructed, based on earlier explorative findings, and was put to a confirmatory test.

METHOD

Items from the Autism Diagnostic Interview-Revised (ADI-R) were used to examine the goodness of fit of the DSM-IV model, the hypothesised symptom model, and two additional models for autism. All models were tested in a group of 255 verbal and nonverbal individuals with minor to severe autistic symptomatology.

RESULTS

The DSM-IV model encountered estimation problems. Conversely, the hypothesised symptom model had no such problems and proved to have a better fit to the sample data than the two additional models for autism. However, some of the observed variables were weak indicators of the three latent factors in the model.

CONCLUSIONS

The hypothesised symptom model appeared to be a plausible model in a group of individuals with a broad range of autistic behaviours and levels of functioning. Nevertheless, the stability of the model needs further examination in a larger group of individuals with disorders in the autism spectrum, and with varying degrees of intellectual functioning.

摘要

背景

多项研究表明,与《精神疾病诊断与统计手册》第四版(DSM-IV)中提及的行为三联征相比,类自闭症谱系障碍的症状结构有所不同。在本研究中,基于早期的探索性发现构建了一个假设的自闭症症状模型,并进行了验证性测试。

方法

使用修订版自闭症诊断访谈(ADI-R)中的项目来检验DSM-IV模型、假设的症状模型以及另外两个自闭症模型的拟合优度。所有模型均在一组255名有轻度至重度自闭症症状的言语和非言语个体中进行测试。

结果

DSM-IV模型遇到了估计问题。相反,假设的症状模型没有此类问题,并且被证明比另外两个自闭症模型更适合样本数据。然而,一些观察变量是该模型中三个潜在因素的弱指标。

结论

在一组具有广泛自闭症行为和功能水平的个体中,假设的症状模型似乎是一个合理的模型。尽管如此,该模型的稳定性需要在更大规模的自闭症谱系障碍个体群体中进一步检验,这些个体具有不同程度的智力功能。

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