Grzadzinski Rebecca, Carr Themba, Colombi Costanza, McGuire Kelly, Dufek Sarah, Pickles Andrew, Lord Catherine
Center for Autism and the Developing Brain, Weill Cornell Medical College, New York-Presbyterian Hospital, 21 Bloomingdale Road, Rogers Building, White Plains, NY, 10605, USA.
Teachers College, Columbia University, New York, NY, USA.
J Autism Dev Disord. 2016 Jul;46(7):2464-79. doi: 10.1007/s10803-016-2782-9.
Psychometric properties and initial validity of the Brief Observation of Social Communication Change (BOSCC), a measure of treatment-response for social-communication behaviors, are described. The BOSCC coding scheme is applied to 177 video observations of 56 young children with ASD and minimal language abilities. The BOSCC has high to excellent inter-rater and test-retest reliability and shows convergent validity with measures of language and communication skills. The BOSCC Core total demonstrates statistically significant amounts of change over time compared to a no change alternative while the ADOS CSS over the same period of time did not. This work is a first step in the development of a novel outcome measure for social-communication behaviors with applications to clinical trials and longitudinal studies.
本文描述了社会沟通变化简短观察量表(BOSCC)的心理测量特性和初始效度,该量表用于测量社会沟通行为的治疗反应。BOSCC编码方案应用于对56名患有自闭症谱系障碍(ASD)且语言能力有限的幼儿的177次视频观察。BOSCC具有高至优异的评分者间信度和重测信度,并与语言和沟通技能测量指标显示出收敛效度。与无变化的对照组相比,BOSCC核心总分随时间推移显示出具有统计学意义的显著变化,而同期的自闭症诊断观察量表(ADOS)社交情感子量表(CSS)则未显示出这种变化。这项工作是开发一种用于社会沟通行为的新型结局测量指标的第一步,该指标可应用于临床试验和纵向研究。