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[胎儿甲状腺肿合并甲状腺功能减退时的正确处理。三例观察报告]

[Correct procedure in the presence of a fetal goiter associated with hypothyroidism. Observations from three cases].

作者信息

Duclos B, Ville Y, Lenclen R, Paupe A

机构信息

Département de gynécologie-obstétrique, hôpital Poissy-Saint-Germain, université Versailles-Saint-Quentin, 10, rue du Champ-Gaillard, 78303 Poissy cedex, France.

出版信息

Gynecol Obstet Fertil. 2006 Jan;34(1):34-7. doi: 10.1016/j.gyobfe.2005.10.027. Epub 2006 Jan 6.

DOI:10.1016/j.gyobfe.2005.10.027
PMID:16406736
Abstract

Fetal goiter is a rare occurrence of which neonatal consequences are not always predictable. Concerning three cases of goiters associated with hypothyroidism discovered in utero, the authors describe the way to take care of in this bad codified situation. They insist upon the major role of ultrasound for goiter diagnosis and its impacts and for control of treatment efficiency. They also discuss intra amniotic L-Thyroxine injection and insist upon the necessity to obtain quick and definite thyroid evaluation after birth before decision to abstain from neonatal therapy.

摘要

胎儿甲状腺肿是一种罕见的情况,其新生儿期后果并非总是可预测的。关于三例在子宫内发现的与甲状腺功能减退相关的甲状腺肿病例,作者描述了在这种规范不足的情况下的处理方法。他们强调超声在甲状腺肿诊断及其影响以及治疗效果控制方面的主要作用。他们还讨论了羊膜腔内注射左甲状腺素,并坚持在决定放弃新生儿治疗之前,出生后必须迅速进行明确的甲状腺评估。

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Antithyroid drug-induced fetal goitrous hypothyroidism.抗甲状腺药物引起的胎儿甲状腺肿性甲状腺功能减退症。
Nat Rev Endocrinol. 2011 Mar 15;7(7):396-406. doi: 10.1038/nrendo.2011.34.