Alfonso-Fischbach A L, Guegan C, Saura R, Maugey-Laulom B, Sandler B, Horovitz J
Service de Gynécologie-Obstétrique B, Hôpital Pellegrin, Bordeaux.
J Gynecol Obstet Biol Reprod (Paris). 1994;23(8):888-91.
We report on a case of fetal goitrous hypothyroidism confirmed by the study of fetal thyroid function. Two injections of intra amniotic levo-thyroxine were performed at 35 and 36 WA. The serial ultra sonographic examination showed the disappearance of the fetal goiter. A healthy baby were delivered by cesarean section at 37 WA. At birth, the thyroid gland was slightly enlarged and the neonatal thyroid hormones were within the normal range. This case suggests that cordocentesis is a reliable method of assessing the status of the fetal thyroid, and that even as early as 35 WA a prenatal treatment of fetal goitrous hypothyroidism is possible by amniocentesis.
我们报告一例经胎儿甲状腺功能研究确诊的胎儿甲状腺肿性甲状腺功能减退症。在孕35周和36周时进行了两次羊膜腔内左甲状腺素注射。系列超声检查显示胎儿甲状腺肿消失。孕37周时通过剖宫产分娩出一名健康婴儿。出生时，甲状腺轻度肿大，新生儿甲状腺激素在正常范围内。该病例表明，脐带穿刺术是评估胎儿甲状腺状况的可靠方法，并且即使早在孕35周，通过羊膜腔穿刺术对胎儿甲状腺肿性甲状腺功能减退症进行产前治疗也是可行的。
