Anagnostopoulos George K, Aithal Guruprasad P, Ragunath Krish, Kaye Philip, Rowlands Brian J
Wolfson Digestive Diseases Centre, Queen's Medical Centre, University Hospital, Nottingham, United Kingdom.
JOP. 2006 Jan 11;7(1):47-50.
Although, squamous metaplasia of the ductal columnar cells can be observed during periods of inflammation, squamous cell pancreatic carcinoma is an extremely rare tumour.
We present the case of a 72-year-old man who presented to our hospital with painless obstructive jaundice. After careful and adequate staging investigations that revealed a malignant mass in the head of pancreas he underwent a laparotomy which revealed an inoperable pancreatic cancer. Palliative bypass procedure was done. The biopsy specimens revealed a squamous cell cancer.
Pure squamous cell carcinoma of the pancreas is a very rare malignancy. In most cases it is not possible to make a pre-operative histological diagnosis and curative resection is unlikely because of dissemination at the time of initial diagnosis or laparotomy.
尽管在炎症期可观察到导管柱状细胞的鳞状化生,但胰腺鳞状细胞癌是一种极其罕见的肿瘤。
我们报告一例72岁男性患者,因无痛性梗阻性黄疸入院。经过仔细且充分的分期检查,发现胰腺头部有一恶性肿块,随后他接受了剖腹手术,结果显示为无法手术切除的胰腺癌。进行了姑息性旁路手术。活检标本显示为鳞状细胞癌。
胰腺纯鳞状细胞癌是一种非常罕见的恶性肿瘤。在大多数情况下,术前无法做出组织学诊断,而且由于在初次诊断或剖腹手术时已发生播散,治愈性切除不太可能。