Brzezińska-Błaszczyk Ewa, Rdzany Rafał S
Zakład Immunologii Doświadczalnej, Uniwersytet Medyczny w Łodzi.
Postepy Hig Med Dosw (Online). 2005;59:544-53.
Nowadays it is well documented that bacteria and/or their products directly or indirectly activate mast cells to secrete mediators and cytokines. These mediators and cytokines induce various effects leading to the development of local inflammation. Moreover, mast cells have the capacity to bind and phagocytose bacteria. What is more, these cells have the capacity to kill bacteria. Thus, mast cells play a pivotal role in host defense, especially in natural immunity, during bacterial infection.
如今，有充分的文献记载表明，细菌和/或其产物直接或间接激活肥大细胞以分泌介质和细胞因子。这些介质和细胞因子会引发各种效应，导致局部炎症的发展。此外，肥大细胞有结合和吞噬细菌的能力。而且，这些细胞有杀死细菌的能力。因此，在细菌感染期间，肥大细胞在宿主防御中，尤其是在天然免疫中发挥着关键作用。
