Koehl Patrice
Nat Chem Biol. 2005 Jul;1(2):71-2. doi: 10.1038/nchembio0705-71.
Prenylation represent a critical step in the biosynthesis of many natural products, A new study reveals how aromatic prenyltransferase enzymes tolerate diverse aromatic polyketides while still controlling the length of prenyl side chains.
异戊烯基化是许多天然产物生物合成中的关键步骤。一项新研究揭示了芳香族异戊烯基转移酶如何在控制异戊烯基侧链长度的同时,耐受多种芳香族聚酮化合物。