Sracic Julie K, Krishnan Ravi S, Nunez-Gussman Janna K, Orengo Ida F, Hsu Sylvia
Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
Dermatol Online J. 2005 Dec 1;11(3):17.
Hereditary papulotranslucent acrokeratoderma is a rare autosomal-dominant syndrome of the hands and feet characterized by persistent, asymptomatic, yellowish to white papules and plaques associated with fine-textured scalp hair and an atopic diathesis. Histopathologically, focal hyperkeratosis, hypergranulosis, and acanthosis of the epidermis are seen. We present a case of hereditary papulotranslucent acrokeratoderma in a young adult woman. The literature of this unusual condition is reviewed, and its relationship to acquired papulotranslucent acrokeratoderma is discussed.
遗传性丘疹性半透明肢端角化病是一种罕见的常染色体显性遗传病，累及手足部位，其特征为持续存在、无症状的淡黄色至白色丘疹和斑块，伴有质地细腻的头皮毛发及特应性素质。组织病理学表现为表皮局灶性角化过度、颗粒层增厚和棘层肥厚。我们报告一例年轻成年女性的遗传性丘疹性半透明肢端角化病病例。本文回顾了关于这种罕见疾病的文献，并讨论了其与获得性丘疹性半透明肢端角化病的关系。
