Blanchard Edward B, Lackner Jeffrey M, Gusmano Rebecca, Gudleski Gregory D, Sanders Kathryn, Keefer Laurie, Krasner Susan
Department of Psychology, Center for Stress and Anxiety Disorders, University of Albany-SUNY, 1400 Washington Avenue, Albany, NY 12222 0001, USA.
Behav Res Ther. 2006 Mar;44(3):317-37. doi: 10.1016/j.brat.2005.01.003. Epub 2006 Jan 18.
Using a sample of over 125 patients with irritable bowel syndrome (IBS) who were treated with cognitive therapy administered in small groups, we sought to predict end of treatment and 3-month follow-up improvement in two changes indices of gastrointestinal (GI) symptoms (Pain/Discomfort Index which assessed change in abdominal pain, abdominal tenderness and bloating and Bowel Regularity Index which assessed change in diarrhea and constipation). We also sought to predict scores on IBS specific quality of life (QOL) and overall level of psychological distress using the Global Severity Index (GSI) of the Brief Symptom Inventory (BSI). Significant, but modest, levels of prediction were found for prediction of improvement in GI symptoms (4-15% of variance). Stronger significant prediction was obtained for the QOL and global psychological distress measure with R(2)'s ranging from 0.36 to 0.50. A wide variety of demographic, GI symptom, psychological status and psychiatric status variables entered the final prediction equations.
我们选取了125多名接受小组认知疗法治疗的肠易激综合征（IBS）患者作为样本，试图预测治疗结束时以及3个月随访时胃肠道（GI）症状两个变化指标（疼痛/不适指数，用于评估腹痛、腹部压痛和腹胀的变化；肠道规律指数，用于评估腹泻和便秘的变化）的改善情况。我们还试图使用简明症状量表（BSI）的总体严重程度指数（GSI）来预测IBS特定生活质量（QOL）得分和心理困扰总体水平。在预测GI症状改善方面发现了显著但适度的预测水平（方差的4 - 15%）。对于QOL和总体心理困扰测量，获得了更强的显著预测，决定系数（R²）范围为0.36至0.50。多种人口统计学、GI症状、心理状态和精神状态变量进入了最终的预测方程。
