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一名老年患者的青少年肌阵挛性癫痫。

Juvenile myoclonic epilepsy in an elderly patient.

作者信息

Jacob Saiju, Martin Darren, Rajabally Yusuf A

机构信息

Department of Neurology, Leicester General Hospital, University Hospitals of Leicester, Leicester LE5 4PW, UK.

出版信息

Age Ageing. 2006 Mar;35(2):194-6. doi: 10.1093/ageing/afj024. Epub 2006 Jan 13.

Abstract

Juvenile myoclonic epilepsy constitutes 5-10% of idiopathic generalised epileptic syndromes. The clinical triad of absence seizures, myoclonic jerks and generalised tonic clonic seizures (GTCS) rarely begin after the second decade of life. We present the case of a 74-year-old lady presenting for the first time with myoclonic jerks and absences. The electro encephalogram revealed generalised polyspike and wave epileptiform activity with photosensitivity. On close questioning, she appeared to have had a single episode of GTCS at the age of 10. She remained asymptomatic for 64 years before the diagnosis was made. Although rare, idiopathic myoclonic epilepsy could remain asymptomatic for decades and can present in the elderly. Proper classification of this epileptic syndrome, even in the elderly, is essential in view of the response to appropriate antiepileptic therapy.

摘要

青少年肌阵挛癫痫占特发性全身性癫痫综合征的5% - 10%。失神发作、肌阵挛抽搐和全身性强直阵挛发作(GTCS)这一临床三联征很少在生命的第二个十年后开始出现。我们报告一例74岁女性首次出现肌阵挛抽搐和失神发作的病例。脑电图显示有广泛性多棘慢波癫痫样活动伴光敏感性。经仔细询问,她在10岁时似乎曾有过一次全身性强直阵挛发作。在确诊前的64年里她一直无症状。尽管罕见,但特发性肌阵挛癫痫可数十年无症状,并可在老年人中出现。鉴于对适当抗癫痫治疗的反应,即使对老年人,正确分类这种癫痫综合征也至关重要。

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