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透视引导下经皮肝穿刺胆道介入操作的辐射剂量与风险

Radiation dose and risk from fluoroscopically guided percutaneous transhepatic biliary procedures.

作者信息

Stratakis John, Damilakis John, Hatzidakis Adam, Perisinakis Kostas, Gourtsoyiannis Nicholas

机构信息

Department of Medical Physics, Faculty of Medicine, University of Crete, P.O. Box 1393, 71409 Iraklion, Crete, Greece.

出版信息

J Vasc Interv Radiol. 2006 Jan;17(1):77-84. doi: 10.1097/01.RVI.0000188754.97465.13.

DOI:10.1097/01.RVI.0000188754.97465.13
PMID:16415136
Abstract

PURPOSE

To estimate radiation dose and associated risks after fluoroscopically guided percutaneous transhepatic biliary (PTB) drainage and stent implantation procedures.

MATERIALS AND METHODS

Organ and effective doses, normalized to dose-area product (DAP), were estimated for PTB procedures with use of a Monte Carlo transport code and an adult mathematical phantom. Exposure parameters from 51 consecutive patients were used to determine average examination parameters for biliary drainage and stent implantation procedures. Thermoluminescent dosimeters were used in an anthropomorphic phantom to verify Monte Carlo calculations. Radiation-induced cancer and genetic risks were estimated.

RESULTS

The results consist of doses normalized to DAP so patient dose from any technique and x-ray unit can be easily calculated for left and right biliary access and for separate or combined biliary and metallic stent implantation sessions. A good agreement was found between Monte Carlo-calculated data and data derived from thermoluminescent dosimetry. The average effective dose varied from 1.8 to 5.4 mSv depending on procedure approach (left vs right access) and procedure scheme. A maximum effective dose of 13 mSv was estimated for 30 minutes of fluoroscopy.

CONCLUSIONS

Doses delivered to patients undergoing PTB procedures are comparable to those that arise from computed tomography protocols. Radiation-induced cancer risk may be considerable for young patients undergoing PTB drainage and stent implantation procedures.

摘要

目的

评估在透视引导下经皮经肝胆道(PTB)引流及支架植入术后的辐射剂量及相关风险。

材料与方法

利用蒙特卡罗传输代码和成人数学体模,对PTB手术的器官剂量和有效剂量进行归一化处理,使其与剂量面积乘积(DAP)相关。使用51例连续患者的曝光参数来确定胆道引流和支架植入手术的平均检查参数。在拟人化体模中使用热释光剂量计来验证蒙特卡罗计算结果。估算辐射诱发癌症和遗传风险。

结果

结果包括归一化至DAP的剂量,因此可根据任何技术和X射线设备轻松计算出左、右胆道通路以及单独或联合进行胆道和金属支架植入手术时的患者剂量。蒙特卡罗计算数据与热释光剂量测定得出的数据之间具有良好的一致性。根据手术入路(左入路与右入路)和手术方案,平均有效剂量在1.8至5.4 mSv之间变化。透视30分钟时估计最大有效剂量为13 mSv。

结论

接受PTB手术的患者所接受的剂量与计算机断层扫描方案产生的剂量相当。对于接受PTB引流和支架植入手术的年轻患者,辐射诱发癌症的风险可能相当大。

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