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累及面部大部分区域的微囊性附属器癌:何时手术不合理?

Microcystic adnexal carcinoma involving a large portion of the face: when is surgery not reasonable?

作者信息

Eisen Daniel Brian, Zloty David

机构信息

Department of Dermatology, University of California, Davis Medical Center, Sacramento, California 95818, USA.

出版信息

Dermatol Surg. 2005 Nov;31(11 Pt 1):1472-7; discussion 1478. doi: 10.2310/6350.2005.31222.

Abstract

BACKGROUND

We report a case of microcystic adnexal carcinoma (MAC) involving a large portion of the face, one of the largest of any MAC reported thus far in this area, and review the literature regarding the nature of the tumor and available treatments. We also review all of the reported cases of metastases and the possible role of radiation in the etiopathogenesis of this tumor.

OBJECTIVE

To review the literature about what is known about therapy for MAC and what options are available to patients who have this disease.

MATERIALS AND METHODS

Case report and review of the literature.

RESULTS

Of the 274 cases of MAC thus far reported, there are 6 cases of metastases, only 1 of which resulted in death.

CONCLUSION

Mohs surgery should be the treatment of choice for this tumor; however, when extirpation entails sufficiently large morbidity, given the low rate of metastases and mortality, observation is a reasonable alternative.

摘要

背景

我们报告一例微囊性附属器癌(MAC)累及面部大部分区域的病例,这是该区域迄今为止报道的最大的MAC病例之一,并回顾了有关该肿瘤性质和现有治疗方法的文献。我们还回顾了所有已报道的转移病例以及放疗在该肿瘤发病机制中的可能作用。

目的

回顾关于MAC治疗的已知文献以及患有这种疾病的患者可选择的治疗方案。

材料与方法

病例报告及文献回顾。

结果

在迄今为止报道的274例MAC病例中,有6例发生转移,其中仅1例导致死亡。

结论

莫氏手术应是该肿瘤的首选治疗方法;然而,当切除带来的发病率足够高时,鉴于转移率和死亡率较低,观察是一种合理的选择。

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