Vleggaar Danny
Clinic for Injectables, The Hague, The Netherlands.
Dermatol Surg. 2005 Nov;31(11 Pt 2):1511-7; discussion 1517-8. doi: 10.2310/6350.2005.31236.
Polymers of lactic acid'have been widely used for many years in different types of medical devices, such as resorbable sutures, intrabone implants, and soft tissue implants. Injectable poly-L-lactic acid (PLLA; Sculptra), a synthetic, biodegradable polymer, has gained widespread popularity in Europe for the treatment of facial changes associated with aging.
To provide background information on injectable PLLA and to describe clinical experience with its use in Europe for facial volume enhancement.
Technique varies with site of injection. Generally, the product is implanted subcutaneously or intradermally in a series of treatments. No allergy testing is required.
Based on experience in more than 2,500 patients, injectable PLLA has been used successfully for the correction of nasolabial folds, mid- and lower facial volume loss, jawline laxity, and other signs of facial aging. Correction lasts for 18 to 24 months in most patients.
Injectable PLLA treatment provides an excellent and prolonged correction of a variety of facial wrinkles, depressions, and laxity with a minimally invasive procedure that does not require allergy testing or a recovery period.
多年来，乳酸聚合物已广泛应用于不同类型的医疗器械，如可吸收缝线、骨内植入物和软组织植入物。可注射聚左旋乳酸（PLLA；Sculptra）是一种合成的可生物降解聚合物，在欧洲已广泛用于治疗与衰老相关的面部变化。
提供有关可注射PLLA的背景信息，并描述其在欧洲用于面部容积增加的临床经验。
技术因注射部位而异。一般来说，该产品通过一系列治疗皮下或皮内植入。无需进行过敏测试。
根据2500多名患者的经验，可注射PLLA已成功用于矫正鼻唇沟、面部中下部容积减少、下颌轮廓松弛及其他面部衰老迹象。大多数患者的矫正效果可持续18至24个月。
可注射PLLA治疗通过一种微创程序，无需过敏测试或恢复期，即可对面部各种皱纹、凹陷和松弛提供出色且持久的矫正效果。
