Marisavljević D, Suvajdzić N, Jovanović V, Kranjcić-Zec I, Bosković D, Colović M
Institute of Haematology, University Clinical Centre, Belgrade.
Srp Arh Celok Lek. 1992 Jan-Feb;120(1-2):65-9.
The authors present two patients with acute myeloid leukaemia and pulmonary-disseminated form of zygomycosis developed during the period of bone marrow aplasia. Diagnosis was established on necropsy on the basic of the patho-histological finding of wide, short and nonseptate hyphe with irregular branching. Hyphe were clearly recognized on Gomori methenamine Silver stained preparations. There were multiple haemorrhagic-necrotic infarcts of different organs due to the mycotic invasion of blood vessels. The authors discuss some some important diagnostic and therapeutic problems.
作者报告了两名急性髓细胞白血病患者，他们在骨髓再生障碍期间发生了肺部播散性接合菌病。根据宽、短且无隔膜、分支不规则的菌丝的病理组织学发现，在尸检时确诊。在Gomori六胺银染色制剂上可清楚识别菌丝。由于真菌侵袭血管，不同器官出现多处出血性坏死梗死。作者讨论了一些重要的诊断和治疗问题。
