Mustaffa-Babjee A, Spradbrow P B
Avian Dis. 1975 Jan-Mar;19(1):150-74.
Three strains of avian adenovirus were isolated and studied in cell cultures, chicken embryos, and chickens. One strain (ADAM-1) was isolated from the bursa of Fabricius of a chicken with Marek's disease, and the others (ADAM-2 and ADAM-3) from one-day-old chicks with respiratory signs. Experimentally, ADAM-1 produced no clinical signs or lesions except atrophy of the bursa of Fabricius. ADAM-2 caused mild respiratory signs in young chickens when inoculated intratracheally. The behavior of the three viruses in cell cultures and chick embryos was similar to that described for other avian adenoviruses (CELO). In a serological survey using the agar-gel precipitation test, 3-30% of sera tested gave a positive reaction.
分离出三株禽腺病毒，并在细胞培养物、鸡胚和鸡中进行研究。一株（ADAM - 1）从患有马立克氏病的鸡的法氏囊中分离得到，其他两株（ADAM - 2和ADAM - 3）从出现呼吸道症状的一日龄雏鸡中分离得到。实验中，ADAM - 1除了导致法氏囊萎缩外，未产生临床症状或病变。ADAM - 2经气管内接种后，在幼鸡中引起轻度呼吸道症状。这三种病毒在细胞培养物和鸡胚中的表现与其他禽腺病毒（CELO）的描述相似。在使用琼脂凝胶沉淀试验的血清学调查中，3% - 30%的检测血清呈阳性反应。
