Müller G, Rahfeld B, Jannasch M
Klinik und Poliklinik für Innere Medizin, Martin-Luther-Universität Halle-Wittenberg.
Z Gesamte Inn Med. 1992 Jun;47(6):263-5.
Malondialdehyde (MDA) level was determined spectrophotometrically with thiobarbituric acid method on 50 healthy persons and 160 patients with alcoholic and nonalcoholic liver diseases. Alcoholics without liver damage show normal plasma MDA values. Alcoholic fatty liver, alcoholic hepatitis and alcoholic liver cirrhosis cause an increase of MDA values. The highest concentrations of MDA were found on patients with acute virus hepatitis. Also noninfectional hepatitis and nonalcoholic liver cirrhosis showed an elevated MDA-Level. Liver damage and lipid peroxidation are considered as closely connected processes.
采用硫代巴比妥酸法通过分光光度法测定了50名健康人和160名酒精性及非酒精性肝病患者的丙二醛（MDA）水平。无肝损伤的酗酒者血浆MDA值正常。酒精性脂肪肝、酒精性肝炎和酒精性肝硬化会导致MDA值升高。急性病毒性肝炎患者的MDA浓度最高。非感染性肝炎和非酒精性肝硬化患者的MDA水平也升高。肝损伤和脂质过氧化被认为是密切相关的过程。
