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[可吸收骨固定材料在大鼠体内诱发肉瘤。初步报告]

[Induction of sarcoma by resorbable osteosynthesis material in the rat. A preliminary report].

作者信息

Hoppert T, Pistner H, Stolte M, Mühling J

机构信息

II. Chirurgische Klinik des Klinikums Bayreuth, Universität Würzburg.

出版信息

Z Orthop Ihre Grenzgeb. 1992 May-Jun;130(3):244-7. doi: 10.1055/s-2008-1040146.

DOI:10.1055/s-2008-1040146
PMID:1642042
Abstract

In an experiment testing the resorption of Poly-l-lactate in the back muscles of Cara rats a foreign body sarcoma occurred in two rats. 20 months after implantation of a body of high molecular weight poly-l-lactate a malignant fibrous histiocytoma developed in one rat. A soft tissue tumor, which was classified according to the immune-histiochemical analysis as a neurogenic sarcoma, developed 23 months after the implantation of a body of injection-casted poly-l-lactate of high molecular weight in a second rat.

摘要

在一项测试聚左旋乳酸在卡拉大鼠背部肌肉中吸收情况的实验中,两只大鼠出现了异物肉瘤。在植入高分子量聚左旋乳酸物体20个月后,一只大鼠发生了恶性纤维组织细胞瘤。在第二只大鼠植入高分子量注射浇铸聚左旋乳酸物体23个月后,出现了一个软组织肿瘤,根据免疫组织化学分析将其分类为神经源性肉瘤。

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