McLaughlin Thomas J, Aupont Onesky, Bambauer Kara Z, Stone Peter, Mullan Mariquita G, Colagiovanni Jane, Polishuk Elaine, Johnstone Michael, Locke Steven E
Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
J Gen Intern Med. 2005 Dec;20(12):1084-90. doi: 10.1111/j.1525-1497.2005.00256.x.
Poor mood adjustment to chronic medical illness is often accompanied by decrements in function.
To evaluate the effectiveness of a telephone-based intervention for psychologic distress and functional impairment in cardiac illness.
Randomized, controlled trial.
We recruited survivors of acute coronary syndromes using the Hospital and Anxiety Depression Scale (HADS) with scores indicative of mood disturbances at 1-month postdischarge. Recruited patients were randomized to experimental or control status. Intervention patients received 6 30-minute telephone counseling sessions to identify and address illness-related fears and concerns. Control patients received usual care. Patients' responses to the HADS and the Workplace Social Adjustment Scale (WSAS) were collected at baseline, 2, 3, and 6 months using interactive voice recognition technology. At baseline, the PRIME-MD was used to establish diagnosis of depression. We used mixed effects regression to study changes in outcomes.
We enrolled 100 patients. Mean age was 60; 67% of the patients were male. Findings confirmed that the intervention group had a 27% improvement in depression symptoms (P=.05), 27% in anxiety (P=.02), and a 38% improvement in home limitations (P=.04) compared with controls. Symptom improvement tracked those for WSAS measures of home function (P=.04) but not workplace function.
The intervention had a moderate effect on patient's emotional and functional outcomes that were observed during a critical period in patients' lives. Patient convenience, ease of delivery, and the effectiveness of the intervention suggest that the counseling can help patients adjust to chronic illness.
对慢性疾病的情绪调节不佳常伴有功能下降。
评估基于电话的干预对心脏病患者心理困扰和功能损害的有效性。
随机对照试验。
我们使用医院焦虑抑郁量表(HADS)招募急性冠脉综合征幸存者,这些幸存者在出院后1个月的得分表明存在情绪障碍。招募的患者被随机分为实验组或对照组。干预组患者接受6次30分钟的电话咨询,以识别并解决与疾病相关的恐惧和担忧。对照组患者接受常规护理。使用交互式语音识别技术在基线、2个月、3个月和6个月时收集患者对HADS和工作场所社会适应量表(WSAS)的反应。在基线时,使用PRIME-MD来确立抑郁症诊断。我们使用混合效应回归来研究结果的变化。
我们纳入了100名患者。平均年龄为60岁;67%的患者为男性。结果证实,与对照组相比,干预组的抑郁症状改善了27%(P = 0.05),焦虑改善了27%(P = 0.02),家庭活动受限改善了38%(P = 0.04)。症状改善与WSAS家庭功能测量结果相符(P = 0.04),但与工作场所功能测量结果不符。
该干预对患者在生命关键时期的情绪和功能结果有中度影响。患者的便利性、易于实施以及干预的有效性表明,咨询可以帮助患者适应慢性病。