Kornblith Alice B, Dowell Jeannette M, Herndon James E, Engelman Beverly J, Bauer-Wu Susan, Small Eric J, Morrison Vicki A, Atkins James, Cohen Harvey Jay, Holland Jimmie C
Breast Oncology Program, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
Cancer. 2006 Dec 1;107(11):2706-14. doi: 10.1002/cncr.22296.
Significant barriers to cancer patients receiving mental health treatment for distress have been reported in the literature. The objective of the current study was to determine whether distress in older patients (aged 65 years and older) would be reduced with educational materials (EM) supplemented by monthly telephone monitoring (TM) (TM + EM) compared with the use of EM alone because of more timely referrals to appropriate health professionals.
One hundred ninety-two older patients with breast, prostate, and colorectal cancers who had advanced disease and currently were receiving treatment were randomized to receive either TM + EM or EM alone. One hundred thirty-one patients were evaluated by telephone interview for psychologic and physical distress and for social support at baseline and at 6 months using the Hospital Anxiety and Depression Scale (HADS), the European Organization for Research and Treatment of Cancer (EORTC)-QLQ-C30 quality-of-life questionnaire, and the Medical Outcomes Study (MOS) Social Support Survey. Patients who in the TM + EM group were called monthly for 6 months to monitor their distress using the HADS and EORTC physical symptom items and the MOS Social Support Survey items, with cutoff levels were established to indicate which patients were in greater distress. Those patients who scored above the cutoff levels were referred to their oncology nurse for referral to the appropriate professional. Patients in the EM group received written materials regarding cancer-related psychosocial issues and available resources.
At 6 months, patients in the TM + EM group reported significantly less anxiety (HADS; P < .0001), depression (HADS; P = .0004), and overall distress (HADS; P < .0001) compared with patients in the EM group.
Monthly monitoring of older patients' distress with TM and EM along with referral for appropriate help was found to be an efficient means of reducing patients' anxiety and depression compared with patients who received only EM.
文献报道癌症患者接受心理健康治疗以缓解痛苦存在重大障碍。本研究的目的是确定与仅使用教育材料(EM)相比,通过每月电话监测(TM)补充教育材料(TM + EM)是否能减轻老年患者(65岁及以上)的痛苦,因为这样能更及时地将患者转介给合适的健康专业人员。
192名患有晚期乳腺癌、前列腺癌和结直肠癌且正在接受治疗的老年患者被随机分为接受TM + EM组或仅接受EM组。在基线和6个月时,通过电话访谈对131名患者进行心理和身体痛苦以及社会支持方面的评估,使用医院焦虑抑郁量表(HADS)、欧洲癌症研究与治疗组织(EORTC)生活质量问卷QLQ - C30以及医学结局研究(MOS)社会支持调查。TM + EM组的患者在6个月内每月接受电话随访,使用HADS和EORTC身体症状项目以及MOS社会支持调查项目监测他们的痛苦情况,并设定临界值以确定哪些患者痛苦程度更高。那些得分高于临界值的患者被转介给肿瘤护士,以便转介给合适的专业人员。EM组的患者收到了有关癌症相关心理社会问题和可用资源的书面材料。
在6个月时,与EM组患者相比,TM + EM组患者报告的焦虑(HADS;P <.0001)、抑郁(HADS;P =.0004)和总体痛苦(HADS;P <.0001)明显更少。
与仅接受EM的患者相比,每月通过TM和EM监测老年患者的痛苦情况并转介获得适当帮助是减轻患者焦虑和抑郁的有效方法。