Kemnitz J, Winter J, Vester E G, Peters J
Abteilungen für Klinische Anaesthesiologie, Heinrich-Heine Universität Düsseldorf, Germany.
Anesthesiology. 1992 Aug;77(2):258-62. doi: 10.1097/00000542-199208000-00006.
In patients with automatic implantable cardioverter defibrillators, insulation of the epicardial patch electrodes (patches) prevents externally applied current from passing through the electrode to the cardiac muscle so that external transthoracic and even internal defibrillation can be unsuccessful. Because emergency cardiac pacing may be required in such a case, a study was performed to evaluate whether, and at what threshold and electrode orientation, transcutaneous pacing is possible in patients with implanted patches. Thresholds for transcutaneous pacing were determined during general anesthesia in nine patients with patches sewn across the heart (anterior right and posterior left ventricles) either before or after surgery, or at both times (automatic implantable cardioverter defibrillator implantation/exchange with or without coronary artery bypass grafting). Because surgery per se can increase the pacing threshold, nine patients of similar body size and weight undergoing routine coronary artery bypass grafting also were evaluated and served as a control group. Pacing thresholds (stimulus duration: 50 ms) were determined during normothermia with a transportable transcutaneous pacer, and adult cutaneous electrodes were placed across the patients' chest in the standard anteroposterior and right-to-left orientations. In all patients with patch electrodes, antero-posterior pacing was possible at a mean threshold of 73 +/- 30 mA standard deviation (range: 40-140 mA). This threshold was not significantly different (Mann-Whitney test) from that in control patients before (57 +/- 20 mA; range: 30-90 mA) or after (94 +/- 24 mA; range: 40-120 mA) coronary artery-bypass grafting. The surgical procedure per se significantly increased the threshold (Wilcoxon test, P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
在植入自动植入式心脏复律除颤器的患者中,心外膜贴片电极(贴片)的绝缘可防止外部施加的电流通过电极传导至心肌,从而导致外部经胸甚至内部除颤可能失败。由于在此类情况下可能需要紧急心脏起搏,因此进行了一项研究,以评估在植入贴片的患者中是否能够进行经皮起搏,以及在何种阈值和电极方向下可行。在9例贴片缝于心脏(右前和左后心室)的患者全麻期间,于手术前或手术后,或两个时间点(植入/更换自动植入式心脏复律除颤器,伴或不伴冠状动脉搭桥术)测定经皮起搏阈值。由于手术本身会增加起搏阈值,因此还评估了9例体型和体重相似、接受常规冠状动脉搭桥术的患者,并将其作为对照组。使用便携式经皮起搏器在常温下测定起搏阈值(刺激持续时间:50毫秒),并将成人皮肤电极以标准的前后位和右至左方向置于患者胸部。在所有有贴片电极的患者中,前后位起搏平均阈值为73±30毫安标准差(范围:40 - 140毫安)时是可行的。该阈值与对照组患者在冠状动脉搭桥术前(57±20毫安;范围:30 - 90毫安)或术后(94±24毫安;范围:40 - 120毫安)相比,差异无统计学意义(曼-惠特尼检验)。手术本身显著增加了阈值(威尔科克森检验,P<0.05)。(摘要截断于250字)