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[促纤维增生性嗜神经性黑色素瘤。一种罕见临床实体的诊断与治疗方法]

[Desmoplastic neurotropic melanoma. Diagnosis and therapeutic procedures for a rare clinical entity].

作者信息

Hauser J, Homann H-H, Drücke D, Kuhnen C, Esenwein S A, Steinau H-U

机构信息

Klinik für Plastische Chirurgie und Schwerbrandverletzte, Handchirurgiezentrum, Operatives Referenzzentrum für Gliedmassentumoren, BG-Kliniken Bergmannsheil Bochum.

出版信息

Chirurg. 2006 Oct;77(10):939-42. doi: 10.1007/s00104-005-1148-1.

Abstract

Desmoplastic neurotropic melanoma is an exceedingly rare variant of the malignant melanomas. Since the initial description, only about 500 cases have been reported in the literature. These melanomas mostly occur on the head, neck, and face, and a wide local excision of the tumor is probably the most important prognostic factor. Therefore, in most cases the tumor resections result in large tissue defects. To gain a good cosmetic result, tissue movement using flaps or grafts will most likely be required to cover the defect. In this paper, a 79-year-old patient with a basal cell carcinoma and desmoplastic melanoma on the scalp is described, and the therapeutic procedure is discussed.

摘要

促纤维增生性嗜神经性黑色素瘤是恶性黑色素瘤中一种极其罕见的变体。自最初描述以来,文献中仅报道了约500例病例。这些黑色素瘤大多发生在头、颈和面部,肿瘤的广泛局部切除可能是最重要的预后因素。因此,在大多数情况下,肿瘤切除会导致大面积的组织缺损。为了获得良好的美容效果,很可能需要使用皮瓣或移植物进行组织移位来覆盖缺损。本文描述了一名79岁头皮患有基底细胞癌和促纤维增生性黑色素瘤的患者,并讨论了治疗方法。

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