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梅尼埃病患者的前庭性跌倒发作或图马金耳石危象

[Vestibular drop attacks or Tumarkin's otolithic crisis in patients with Meniere's disease].

作者信息

Morales Angulo C, Gallo-Terán J

机构信息

Servicio de ORL, Hospital Sierrallana, Torrelavega, Cantabria.

出版信息

Acta Otorrinolaringol Esp. 2005 Dec;56(10):469-71. doi: 10.1016/s0001-6519(05)78650-7.

DOI:10.1016/s0001-6519(05)78650-7
PMID:16425641
Abstract

INTRODUCTION

Drop attacks (DA) are a sudden fall that comes without warning and without loss of consciousness, with no associated neurological symptoms and normal neurological examination. A certain number of patients with Meniere's disease, develop Tumarkin's otolithic crisis or DA. The purpose of this study is to document the frequency and clinical features of DA in patients with Meniere's disease.

METHODS

A cohort of 40 patients with "definitive" Meniere's Disease were followed up between six months and 12 years. The presence and characteristics of Tumarkin's otolithic crisis were recorded.

RESULTS

Thirteen (32.5%) patients developed DA during the outcome of their Meniere's disease. The interval between the onset of typical symptoms of Meniere's disease and the DA ranged from less than one year to 18 years. The number of DA varied from 1 to 14. The attacks typically occurred in a flurry during a period of 1 year or less. Six patients had only one DA. No patient requiered treatment for the DA.

CONCLUSIONS

Tumarkin's otolithic crisis in Meniere's disease are not uncommon. They can occur at any time during the course of the disease, generally in a flurry of less than one year. Most patients have a spontaneus remission of the DA.

摘要

引言

跌倒发作(DA)是一种毫无征兆且无意识丧失的突然跌倒,无相关神经症状且神经学检查正常。一定数量的梅尼埃病患者会出现图马尔金耳石危象或跌倒发作。本研究的目的是记录梅尼埃病患者中跌倒发作的频率和临床特征。

方法

对40例“确诊”梅尼埃病患者进行了为期6个月至12年的随访。记录了图马尔金耳石危象的存在情况和特征。

结果

13例(32.5%)患者在梅尼埃病病程中出现了跌倒发作。梅尼埃病典型症状出现至跌倒发作的间隔时间从不到1年至18年不等。跌倒发作的次数从1次到14次不等。发作通常在1年或更短时间内集中出现。6例患者仅有1次跌倒发作。没有患者因跌倒发作需要治疗。

结论

梅尼埃病中的图马尔金耳石危象并不罕见。它们可在疾病过程中的任何时间发生,通常在不到1年的时间内集中出现。大多数患者的跌倒发作会自发缓解。

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Acta Otorrinolaringol Esp. 2005 Dec;56(10):469-71. doi: 10.1016/s0001-6519(05)78650-7.
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Vestibular Drop Attack: An Analysis of the Therapeutic Response.前庭性跌倒发作:治疗反应分析
Audiol Res. 2023 Dec 27;14(1):27-34. doi: 10.3390/audiolres14010004.
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Otolithic membrane damage in patients with endolymphatic hydrops and drop attacks.内淋巴积水和发作性倾倒患者的耳石膜损伤。
Otol Neurotol. 2012 Dec;33(9):1593-8. doi: 10.1097/MAO.0b013e318271c48b.
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[Menière's disease : evidence and controversies].[梅尼埃病:证据与争议]
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