Kern R S, Van Gorp W G, Cummings J L, Brown W S, Osato S S
Fuller Graduate School of Psychology, VA Medical Center West Los Angeles.
Brain Cogn. 1992 Jul;19(2):172-82. doi: 10.1016/0278-2626(92)90043-l.
Confabulation is present when memory is disturbed, but does it occur in Alzheimer's disease (AD) where memory abnormalities are often severe? In this study, confabulation was assessed prospectively in 26 AD patients and 15 normal elderly (NE) controls using a neuropsychological battery specifically designed to assess different types of memory errors. The results indicated that the AD group made significantly more verbal intrusions than the NE group. These findings provide evidence for the feasibility of eliciting confabulatory-type behavior during clinical assessment and support previous reports which have documented verbal intrusions as a common accompaniment of the memory impairment manifested by AD patients.
当记忆受到干扰时会出现虚构，但它会发生在记忆异常往往很严重的阿尔茨海默病（AD）中吗？在本研究中，使用专门设计用于评估不同类型记忆错误的神经心理测验组，对26例AD患者和15名正常老年人（NE）对照进行了前瞻性虚构评估。结果表明，AD组的言语侵入明显多于NE组。这些发现为在临床评估期间引发虚构型行为的可行性提供了证据，并支持了先前的报告，这些报告记录了言语侵入是AD患者记忆障碍的常见伴随症状。
