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[口腔扁平苔藓白色念珠菌分离株对颊黏膜上皮细胞的黏附作用]

[Adhesion to buccal epithelial cells of Candida albicans isolates from oral lichen planus].

作者信息

Zeng Xin, Chen Qian-ming, Nie Min-hai, Li Bing-qi

机构信息

Dept of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2005 Dec;23(6):537-8.

PMID:16430191
Abstract

OBJECTIVE

To investigate the adhesion to buccal epithelial cells of Candida albicans isolates from erosive oral lichen planus (OLP) and nonerosive OLP, and its role in the development of OLP.

METHODS

A total of 112 isolates, comprising healthy control (26), erosive OLP (62) and nonerosive OLP (24), were screened for the adhesion by using buccal epithelial cell (BEC) assay.

RESULTS

The adhesion to buccal epithelial cells of the isolates from erosive OLP group was stronger than that of those from healthy control.

CONCLUSION

Candida albicans, some isolates with a special virulence attribute may contribute to the occurrence and progression of erosive OLP.

摘要

目的

研究从糜烂性口腔扁平苔藓(OLP)和非糜烂性OLP中分离出的白色念珠菌对颊黏膜上皮细胞的黏附作用及其在OLP发病中的作用。

方法

采用颊黏膜上皮细胞(BEC)试验,对总共112株分离菌进行黏附筛选,其中包括健康对照(26株)、糜烂性OLP(62株)和非糜烂性OLP(24株)。

结果

糜烂性OLP组分离菌对颊黏膜上皮细胞的黏附力强于健康对照组。

结论

白色念珠菌,一些具有特殊毒力属性的分离株可能在糜烂性OLP的发生和发展中起作用。

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