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宫角妊娠:一项系统文献综述及一种新型治疗方案的两例病例报告

Cornual gestation: a systematic literature review and two case reports of a novel treatment regimen.

作者信息

Ross Reneita, Lindheim Steven R, Olive David L, Pritts Elizabeth A

机构信息

Department of Obstetrics and Gynecology, University of Wisconsin, Madison, USA.

出版信息

J Minim Invasive Gynecol. 2006 Jan-Feb;13(1):74-8. doi: 10.1016/j.jmig.2005.11.005.

DOI:10.1016/j.jmig.2005.11.005
PMID:16431329
Abstract

STUDY OBJECTIVE

To introduce a novel tubal-sparing regimen for the treatment of nonruptured cornual pregnancies.

DESIGN

Case report and systematic review of the literature.

SETTING

Tertiary Care University setting.

PATIENTS

Two patients referred for care in our subspecialty clinic.

INTERVENTIONS

Laparoscopic surgery, dilation and evacuation, and postoperative methotrexate injection. Systematic review of the literature.

MEASUREMENTS AND MAIN RESULTS

Both medical and surgical treatments for cornual gestation exist; however, each is not without its shortcomings. Medical treatment is associated with failure rates that may result in uterine rupture and catastrophic hemorrhage. Surgical treatment that involves hysterectomy causes a loss of future childbearing capability. Surgical treatment that involves resection of the involved cornual region is associated with decreased fertility rates and increased rates of uterine rupture in future pregnancies. Our treatment regimen is safe and effective and conserves future fertility.

CONCLUSION

A cornual gestation is one of the most hazardous types of ectopic gestation. The diagnosis and treatment of such a pregnancy is challenging and constitutes an urgent medical situation. We herein introduce a novel regimen for the treatment of nonruptured cornual pregnancies. The existing treatment regimens are also systematically reviewed.

摘要

研究目的

介绍一种用于治疗未破裂宫角妊娠的新型保留输卵管方案。

设计

病例报告及文献系统综述。

地点

三级医疗大学附属医院。

患者

两名患者转诊至我们的专科门诊接受治疗。

干预措施

腹腔镜手术、刮宫术及术后甲氨蝶呤注射。文献系统综述。

测量指标及主要结果

宫角妊娠的药物治疗和手术治疗均存在,但每种方法都有其不足之处。药物治疗的失败率可能导致子宫破裂和灾难性出血。涉及子宫切除术的手术治疗会导致未来生育能力丧失。涉及切除受累宫角区域的手术治疗与未来妊娠的生育率降低和子宫破裂率增加有关。我们的治疗方案安全有效,并能保留未来生育能力。

结论

宫角妊娠是最危险的异位妊娠类型之一。此类妊娠的诊断和治疗具有挑战性,构成紧急医疗情况。我们在此介绍一种治疗未破裂宫角妊娠的新型方案。同时也对现有治疗方案进行了系统综述。

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引用本文的文献

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Cornual Pregnancy: Results of a Single-Center Retrospective Experience and Systematic Review on Reproductive Outcomes.宫角妊娠:单中心回顾性研究结果及生殖结局的系统评价
Medicina (Kaunas). 2024 Jan 21;60(1):186. doi: 10.3390/medicina60010186.
2
Hysteroscopic resection as a safe minimally invasive technique for the management of cornual pregnancy: A case report and literature review.宫腔镜切除术作为治疗宫角妊娠的一种安全微创技术:病例报告及文献综述
Clin Case Rep. 2023 Nov 8;11(11):e8137. doi: 10.1002/ccr3.8137. eCollection 2023 Nov.
3
Multidose methotrexate treatment of cornual pregnancy after in vitro fertilization: Two case reports.
体外受精后宫角妊娠的多剂量甲氨蝶呤治疗:两例报告
Case Rep Womens Health. 2021 Dec 14;33:e00376. doi: 10.1016/j.crwh.2021.e00376. eCollection 2022 Jan.
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Management of interstitial pregnancy in the era of laparoscopy: a meta-analysis of 855 case studies compared with traditional techniques.腹腔镜时代间质部妊娠的管理:855例病例研究与传统技术对比的荟萃分析
Obstet Gynecol Sci. 2021 Mar;64(2):156-173. doi: 10.5468/ogs.20299. Epub 2021 Feb 4.
5
Intact Left Cornual Ectopic Pregnancy: A Case Report.左侧宫角完整型异位妊娠:一例报告
Oman Med J. 2013 Jul;28(4):e053. doi: 10.5001/omj.2013.87.
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Interstitial Pregnancy: From Medical to Surgical Approach-Report of Three Cases.间质部妊娠:从保守治疗到手术治疗——三例报告
Case Rep Obstet Gynecol. 2018 Oct 15;2018:2815871. doi: 10.1155/2018/2815871. eCollection 2018.
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Treatment of cornual pregnancy in a patient with adenomyosis by high-intensity focused ultrasound (HIFU) ablation: A case report.高强度聚焦超声(HIFU)消融治疗子宫腺肌病患者的宫角妊娠:一例报告。
Medicine (Baltimore). 2017 Dec;96(48):e8874. doi: 10.1097/MD.0000000000008874.
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Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review.输卵管及非输卵管异位妊娠的发病率、诊断与管理:综述
Fertil Res Pract. 2015 Oct 15;1:15. doi: 10.1186/s40738-015-0008-z. eCollection 2015.
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