成人斯蒂尔病中模拟T细胞淋巴瘤的淋巴结组织学表现
Lymph node histology simulating T-cell lymphoma in adult-onset Still's disease.
作者信息
Reichert L J, Keuning J J, van Beek M, van Rijthoven A W
机构信息
Department of Internal Medicine, University Hospital St. Radboud, Nijmegen, The Netherlands.
出版信息
Ann Hematol. 1992 Jul;65(1):53-4. doi: 10.1007/BF01715128.
A patient with adult-onset Still's disease (AOSD) underwent lymph node biopsy as part of initial evaluation for fever of unknown origin. The lymph node histology showed a massive, diffuse immunoblastic hyperplasia, simulating T-cell lymphoma. This nodal histology differs from rheumatoid arthritis, where mostly a follicular B-cell reaction predominates. Evaluating fever of unknown origin when one is unacquainted with this massive immunoblastic hyperplasia can lead to the wrong diagnosis of T-cell lymphoma in patients with AOSD.
一名成年起病型斯蒂尔病（AOSD）患者接受了淋巴结活检，作为不明原因发热初始评估的一部分。淋巴结组织学显示大量弥漫性免疫母细胞增生，类似T细胞淋巴瘤。这种淋巴结组织学与类风湿关节炎不同，类风湿关节炎中主要是滤泡性B细胞反应占主导。当不熟悉这种大量免疫母细胞增生时，对不明原因发热进行评估可能会导致对AOSD患者错误诊断为T细胞淋巴瘤。
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