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[病态窦房结综合征]

[Sick sinus syndrome].

作者信息

De Roy L

机构信息

Université de Louvain (UCL), unité de rythmologie des cliniques universitaires de Mont-Godine, avenue Docteur Gaston Therasse 1, B - 5530 Yvoir, Belgique.

出版信息

Arch Mal Coeur Vaiss. 2005 Dec;98 Spec No 5:42-7.

Abstract

Sick sinus syndrome is an association of sinus node dysfunction with bradycardia, pauses, sino-atrial block, chronotropic insufficiency and atrial arrhythmias. The diagnosis is essentially clinical and electrocardiographic. Prolonged ECG recordings allow a better assessment of the severity of the condition whereas electrophysiological investigations only provide complementary information which is rarely decisive in the therapeutic indications. Cardiac pacing is the treatment of choice for symptomatic patients: significant improvement in symptoms may be expected but there is no significant change in survival. Single chamber atrial stimulation or dual chamber pacing is preferable to single chamber ventricular pacing, especially with regards to the incidence of atrial fibrillation and the impact on quality of life.

摘要

病态窦房结综合征是窦房结功能障碍与心动过缓、停搏、窦房阻滞、变时性功能不全及房性心律失常相关联的一种疾病。诊断主要依靠临床症状和心电图检查。长时间的心电图记录有助于更好地评估病情严重程度,而电生理检查仅提供补充信息,在治疗指征方面很少起决定性作用。心脏起搏是有症状患者的首选治疗方法:症状有望得到显著改善,但生存率并无显著变化。单腔心房刺激或双腔起搏优于单腔心室起搏,尤其是在房颤发生率及对生活质量的影响方面。

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