Serebrianskaia M V, Fokina T S, Maksimova I E
Ross Med Zh. 1992(2):16-9.
The paper is concerned with evaluation of the activity of the intracellular enzymes of lymphocytes--succinate dehydrogenase and alpha-glycerophosphate dehydrogenase of mitochondria, in patients with peptic ulcer running a different course to define their importance in the disease prediction. Aggravation of peptic ulcer was found to result at first in marked activation of lymphocyte energy supply including that at the expense of the formation of new cellular populations. Later the count of lymphocytes with a high enzymatic activity was found to decline together with a reduction of enzymatic activity. The retention of the indicated changes after ulcer healing serves a prognostically unfavourable sign of the further disease course.
本文关注的是对消化性溃疡病情发展不同的患者淋巴细胞内酶——线粒体琥珀酸脱氢酶和α-甘油磷酸脱氢酶的活性进行评估,以确定它们在疾病预测中的重要性。发现消化性溃疡病情加重首先会导致淋巴细胞能量供应显著激活,包括通过形成新的细胞群体来实现。随后发现酶活性高的淋巴细胞数量会随着酶活性的降低而减少。溃疡愈合后这些变化持续存在是疾病进一步发展预后不良的迹象。