Ortega Trujillo José R, Suárez de Lezo Herreros de Tejada Javier, García Quintana Antonio, Melián Nuez Francisco, Rodríguez Delgado Raquel, Medina Fernández-Aceytuno Alfonso
Servicio de Cardiología, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.
Rev Esp Cardiol. 2006 Jan;59(1):78-81.
Platypnea-orthodeoxia is a rare syndrome characterized by the occurrence of dyspnea and hypoxemia on adoption of an upright posture (i.e., orthodeoxia) and by the absence of symptoms and hypoxemia in decubitus. This syndrome is frequently related to patent foramen ovale and right-to-left shunting. We describe two patients in whom patent foramen ovale with right-to-left shunting was observed on transthoracic and transesophageal echocardiography and who had platypnea-orthodeoxia in the absence of pulmonary disease. They underwent transcatheter closure using an Amplatz device. The echocardiographic diagnosis and closure procedure are discussed. These case reports demonstrate that closure of patent foramen ovale is an effective treatment for platypnea-orthodeoxia.
直立性呼吸困难-卧位低氧血症是一种罕见综合征，其特征为采取直立姿势时出现呼吸困难和低氧血症（即卧位低氧血症），而卧位时无症状和低氧血症。该综合征常与卵圆孔未闭及右向左分流有关。我们描述了两名患者，经胸和经食管超声心动图检查发现卵圆孔未闭伴右向左分流，且在无肺部疾病的情况下患有直立性呼吸困难-卧位低氧血症。他们使用Amplatz装置进行了经导管封堵。讨论了超声心动图诊断及封堵过程。这些病例报告表明，卵圆孔未闭封堵术是治疗直立性呼吸困难-卧位低氧血症的有效方法。
