Dyb Grete, Holmen Turid Lingaas, Zwart John-Anker
Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Neurology. 2006 Jan 24;66(2):198-201. doi: 10.1212/01.wnl.0000193630.03650.19.
To examine the association between the use of analgesics and primary headache disorders (i.e., migraine and tension-type headache) among adolescents in relation to age, gender, and headache frequency.
This cross-sectional, population-based study was conducted in Norway from 1995 to 1997. The total study population consisted of 5,471 adolescents, 13 to 18 years of age, who were interviewed about their headache complaints and completed a comprehensive questionnaire including use of analgesics.
The prevalence of daily headache associated with analgesic use was 0.5%, with a higher rate for girls (0.8%) than for boys (0.2%). There was a significant association for both genders between analgesic use and headache, although most pronounced for migraine. There was a significant linear relationship between analgesic use and headache frequency. Analgesic use was more common among girls than boys and increased with age both for those with and those without headache.
The use of analgesics is common among adolescents with headache, especially among girls. Although this study did not directly evaluate for medication-overuse headache, the trend of frequent analgesic use suggests this possibility. Parents and physicians should increase their awareness of potential analgesic overuse, especially among adolescents with frequent headache.
探讨青少年使用镇痛药与原发性头痛疾病（即偏头痛和紧张型头痛）之间的关联，以及年龄、性别和头痛频率之间的关系。
这项基于人群的横断面研究于1995年至1997年在挪威进行。总研究人群包括5471名13至18岁的青少年，他们接受了关于头痛症状的访谈，并完成了一份包括镇痛药使用情况的综合问卷。
与使用镇痛药相关的每日头痛患病率为0.5%，女孩（0.8%）高于男孩（0.2%）。镇痛药使用与头痛在两性中均存在显著关联，尽管在偏头痛中最为明显。镇痛药使用与头痛频率之间存在显著的线性关系。女孩比男孩更常使用镇痛药，且无论有无头痛，使用频率均随年龄增长而增加。
使用镇痛药在有头痛的青少年中很常见，尤其是女孩。尽管本研究未直接评估药物过量使用性头痛，但频繁使用镇痛药的趋势提示了这种可能性。家长和医生应提高对潜在镇痛药过度使用的认识，尤其是在头痛频繁的青少年中。
